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Lotrel, generically known as amlodipine and benazepril, is a medication used to treat hypertension. It works by relaxing the blood vessels and reduce the activities that contribute to the heart’s workload.

Things To Consider Before Taking Lotrel

Consult the doctor before planning to take Lotrel, or any other related medications. Lotrel is not suitable for everyone, and there are other patients who may manifest some allergic reactions such as swelling of the facial and mouth area, as well as the airways. Patients who consider Lotrel as one of their options for treatment should discuss with their doctor current medications, as well as medical, drug and allergy history.

Those with  liver disease, diabetes, kidney disease, collagen vascular disorders, or additional conditions involving the heart might need special monitoring, testing, or care if taking Lotrel, or may not be able to take it at all.

Lotrel is also not suitable for pregnant and nursing women, as it is reported to have a serious effect on unborn babies, and on babies who rely on breastfeeding. Those who are pregnant, or thinking they might be pregnant, and nursing babies should not be given this medication.

Lotrel is also known to have negative interaction with certain medications. Thus, patients should openly discuss any current medications, whether it is an over the counter or prescription medication, herbal remedies or vitamin supplement.

Medication such as diuretics, potassium supplements, lithium and other similar medications are more likely to cause negative interactions with Lotrel. Alcohol, salt substitutes, or anything that contains potassium should be avoided during , as these contribute to drop in blood pressure as well as dehydration. When a patient takes Lotrel, liquid intake should be increased.

What To Do In An Overdose

Lotrel can become fatal when taken in large doses. An overdose of this medication should be immediately reported for prompt medical treatment. A patient is known to be overdosed by Lotrel if there are any manifestations of chest pain, slurred speech, shortness of breath, dizziness, confusion and many others, including coma and death. However, these signs are similar as to the mild side effects associated with taking the medication. Thus, it is REALLY important to tell the doctor if there are any unusual changes noticed after taking Lotrel.

Lotrel Dosage And Administration

Lotrel is available in these doses: 2.5-10mg, 5-40mg, 5-10mg capsules, 5-20mg, 10-20mg, and 10-40mg capsules. Doctors assess the patient’s current condition, together with the medical, drug and allergy history before prescribing a dose and certain schedule.

In the event that a patient misses a scheduled dose, it is better to take the next one without having the dose doubled. Doing so will increase the likelihood of the patient to experience an overdose.

Side Effects

Lotrel, just like other medications, has its set of side effects that range from mild, moderate up to severe. During treatment, patients might encounter any of these reactions: swelling of the facial and mouth area including the airways, which may lead into difficulty in breathing. There are other side effects which should be immediately reported to the doctor: irregular heartbeat, fainting and dizziness, chest pain, unusually slow or fast heart rate, decrease in urine and the like.

Mild side effects such as dry cough, insomnia, headaches, sluggishness, diarrhea, and the like could be relieved by reducing the usual dose of Lotrel.

Other Details

Lotrel has the molecular formula C20H25ClN2O5 and the IUPAC name methylethyl2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6- methyl-1,4-dihydropyridine-3,5-dicarboxylate. It weighs at 408.876 g/mol. Other brand names of Lotrel are: Norvasc, Lipinox, Coroval, Amvaz, Amlodis, Amlodipinum, Amlodipino, and Amlocard.

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